Abstract

The inhibition of the oxidation reaction through dietary therapy is expected to prevent from the emergence of metabolic disorder e.g. obesity-related complications, insulin resistance, and dyslipidemia. One of the food commodities that can be utilized is rice bran due to oryzanol content. The objective of this study was to analyze the effect of intervention of ricebran oil (RBO) emulsion beverageon inflammatory biomarkers of High SensitivityC-Reactive Protein (Hs CRP) and Interleukin-6(IL-6) among metabolic syndrome (MS) adult subjects. This study used a randomized single blind controlled trial design. Thirty five adult subjects (age 34-57 years) with MS are divided into 2 groups. Treatment group (n = 18) was given RBO emulsion beverage for 4 weeks. The control group (n = 17) was given placebo emulsion beverage (withoutRBO). Nutrition in take was assessed by 24 hours recalls method everyweek. HsCRP and IL-6 levels were analyzed at pre and postintervention. After 4 weeks intervention, there was a significant change of the HsCRP level (p<0.05) in both groups, while for IL-6 serum levels a significant change only in control groups. However, the level of HsCRP and IL-6 serumin the treatment group no significant difference (p>0.05). The intervention of rice bran oilseems give benefit for inflammation state on MS subject.

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