Abstract

Objective To investigate the clinical effect of applying atropine and neosynephrine to prevent intraoperative floppy iris syndrome during age-related cataract surgery in high risk patients. Methods Six hundred and forty-one eyes of 596 patients receiving age-related cataract surgery in our hospital from Jan.2012 to Dec.2013 were analysed.The past history of illness and drug history before the surgery were enquired. 50 patients(52 eyes) that had benign prostatic hyperplasia in 2013 and used tamsulosin and finasteride were applied with atropine and neosynephrine. Patients of the same history in 2012 had not applied atropine or neosynephrine. The incidence of intraoperative floppy iris syndrome during surgery between patients in 2013 and 2012 were compared. Results The intraoperative floppy iris syndrome occurred in 10 eyes(2.95%) in 2012 and 2 eyes(0.66%) in 2013, the difference was statistically significant (P<0.05). Conclusion Atropine and neosynephrine can be applied in patients with high risk of intraoperative floppy iris syndrome, to prevent its occurance during age-related cataract surgery. Key words: Cataract, age-related; Floppy iris syndrome, senile; Atropine; Neosynephrine; Prevention

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