Abstract

In this study, sodium alginate-based thin films were modified by the addition of tannic acid. Materials were obtained by solvent evaporation. They were characterized by the observation of its morphology and its surface by scanning electron microscope and atomic force microscope. The thermal properties were studied by differential scanning calorimetry. The concentration of tannic acid released from the material was determined by the Folin–Ciocalteu method. The material safety for biomedical application was determined by the hemolysis rate study in contact with sheep blood as well as platelet adhesion to the material surface. Based on the obtained results, we assume that proposed films based on sodium alginate/tannic acid are safe and may potentially find application in medicine.

Highlights

  • Synthetic products, including polymers, vary in their fate and their repetitive properties

  • The highest roughness was noticed for the film based on pure sodium alginate (Table 1)

  • The addition of tannic acid smoothed the surface, displayed by lower roughness parameters compared to 100SA (Figure 3)

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Summary

Introduction

Synthetic products, including polymers, vary in their fate and their repetitive properties. Because the tread with fossil fuel is maintained, their overall use worldwide has a negative impact on the environment [1]. Trends take into account the environment derived from natural sources and what benefits will be derived in the coming years [2]. Polysaccharides are polymeric carbohydrate structures of simple sugars (monosaccharides) linked together by glycosidic bonds. They are the most common natural product produced by plants and fungi [3]. Based on the structural composition, we can distinguish homoglycans—polysaccharides made of one type of monomer—and heteroglycans made of several types of monomers [4]

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