Abstract
HLA population study was performed in asthmatic children. The frequencies of HLA class I (A, B, C), II (DR, DQ, DRW) antigens were measured in the following groups. Forty-eight asthmatic children, aged 5-17 years, were diagnosed by clinical manifestation alone. Thirty-one asthmatic children, aged 5-16 years, were diagnosed by clinical manifestation and high serum level of DF-specific IgE antibody, Fifty-two healthy control group, aged 15-45 years, were documented by absence of symptoms, negative DF specific IgE antibody and negative DF skin test. Our results suggest no significant difference in the frequency of HLA antigen in the 3 groups.
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More From: Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology
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