Abstract
To study cognitive dysfunction and brain electrical activity in sleep-wakefulness cycle in patients with frontal lobe tumors. Twenty patients, aged 48.6±4.2 years, and ten healthy volunteers participated in the study. The first group included patients without cognitive impairment and tumors 8.9±5.1 cm3, the second group included patients with cognitive impairment and tumors 40.7±2.1 cm3. The battery of cognitive impairment tests was used. The EEG of wakefulness and night sleep was recorded. Cognitive impairment in patients with lobe tumors is associated with increases in delta/theta, and areactivity of the cortex in wakefulness, increases in delta/theta/alpha in REM and declining number of arousals in REM. The results of the study may be useful in early detection of biomarkers of the cognitive impairment in patients with frontal lobe tumors in order to increase the efficiency of rehabilitation of patients.
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