The study about the difference of extra cellular volume calculated with T1mapping in dilated cardiomyopathy with and without late gadolinium enhancement

Kunihiko Teraoka,Yoshinori Suzuki,Yoshiaki Komori

doi:10.1186/1532-429x-17-s1-p306

Abstract

Background It is well known that the DCM patients having Late Gadolinium Enhancement at Mid-layer of LV septal wall (Mid-LGE) shows poor prognosis compared to the case not having Mid-LGE However, about the other histopathological differences by the existence of Mid-LGE, it is not clear. On the other hand, in recent years, it became possible to calculate ECV from measurement of T1 value of the myocardium before and after of enhanced imaging which used the Modified Look-Locker Inversion Recovery(MOLLI) method, and the usefulness in the quantitative evaluation of histopathological changes, such as diffuse fibrosis observed in hypertrophic cardiomyopathy, has been reported. We will study about the difference of extra cellular volume(ECV) calculated with T1mapping in DCM with and without LGE

Highlights

It is well known that the DCM patients having Late Gadolinium Enhancement at Mid-layer of LV septal wall (Mid-LGE) shows poor prognosis compared to the case not having Mid-LGE
In recent years, it became possible to calculate ECV from measurement of T1 value of the myocardium before and after of enhanced imaging which used the Modified Look-Locker Inversion Recovery(MOLLI) method, and the usefulness in the quantitative evaluation of histopathological changes, such as diffuse fibrosis observed in hypertrophic cardiomyopathy, has been reported
ECV was computed from T1 value and hematocrit value of each area on before and after enhancement, and were taken as the median value of each measured value of a septum area, areas other than a septum, and all the sections were calculated

Summary

Introduction

It is well known that the DCM patients having Late Gadolinium Enhancement at Mid-layer of LV septal wall (Mid-LGE) shows poor prognosis compared to the case not having Mid-LGEabout the other histopathological differences by the existence of Mid-LGE, it is not clear.On the other hand, in recent years, it became possible to calculate ECV from measurement of T1 value of the myocardium before and after of enhanced imaging which used the Modified Look-Locker Inversion Recovery(MOLLI) method, and the usefulness in the quantitative evaluation of histopathological changes, such as diffuse fibrosis observed in hypertrophic cardiomyopathy, has been reported.We will study about the difference of extra cellular volume(ECV) calculated with T1mapping in DCM with and without LGE. The study about the difference of extra cellular volume calculated with T1mapping in dilated cardiomyopathy with and without late gadolinium enhancement Background It is well known that the DCM patients having Late Gadolinium Enhancement at Mid-layer of LV septal wall (Mid-LGE) shows poor prognosis compared to the case not having Mid-LGE

Results

Conclusion