Abstract
I started my medical career as medical mycologist following the first case of deep-seated candidiasis in Japan. On the other hand I have been seeing many patients with tuberculosis as well as respiratory diseases. In my sense the seeing of mycobacterial infections may still remain lot of clinical, biological or immunological research ideas in future. I did the studies on muramyl dipeptide (MDP) which derived from cell wall substance of mycobacteria. MDP seemed to be one of the enhancing immunomodulator for host defense mechanism in particular in the immunocompromised host.
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