Abstract

Prostaglandin Bx (PGBx), a complex mixture of closely related oligomers of Prostaglandin B1 (PGB1) or 15-dehydro-PGB1 which has unique biological activities, is formed under basic conditions. For mechanistic studies of the oligomerization, two dimers of 15-dehydro-PGB1 were prepared under mild conditions and their structures were determined by means of nuclear magnetic resonance (NMR) spectroscopic studies.

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