Abstract

Cell membrane receptors play a key role in regulating cell communication and maintaining cell homeostasis. This paper explores the complex relationship between the structure and function of cell membrane receptors, and elucidates their multiple roles in signal transduction, cellular response, and disease pathways. Different receptor types, including as G protein-coupled receptors (GPCRs), ligand-gated ion channels, receptor tyrosine kinases (RTKs), and cytokine receptors, have varied structural properties that serve different biological purposes and are necessary for cell division, proliferation, and metabolism. The function of membrane receptors that translate extracellular signals into intracellular responses is diverse. The organization of lipid rafts and other receptors within membrane microdomains can influence signal transduction efficiency and specificity. There are inseparable interactions among receptor internalization, recycling and degradation, and regulating the duration and intensity of receptor signaling is closely related to the treatment of diseases. In summary, the current research status of cell membrane receptor structure and function is reviewed in this paper. It contributes to a broader understanding of how receptors regulate important cellular processes at the molecular level. Understanding the nuances of receptor structure-function relationships holds great promise for developing new therapeutic strategies and advancing drug discovery for a variety of diseases.

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