Abstract

AbstractAccumulating evidence shows that the central nervous system (CNS) regulates the activity of the immune system. Concerning the role of immune system in cancer, psychosocial influences on immune function provide a mechanism of association between psychosocial factors (like interpersonal aggression) and cancer prognosis. Social conflicts between males, involving high aggression stress and threat (psychosocial conflicts) produce both an allostatic state and allostatic load. The costs for aggressors (Hawks) and victims (losers) tested under semi laboratory conditions are quite different. Testosterone does not cause aggression, only exaggerates the pre-existing pattern and response to environmental triggers of aggression. The individual's personality type (authoritarian Hawk or Dove) has major impact on psychoneuroimmune mechanisms linking aggression stress through inflammation to cancer. Due to the latest connotations we propose this personality phenomenon label as "the Strauss-Kahn syndrome".

Highlights

  • Unemotional violence associated with aggression stress is often called ‘predatory’ because it involves a restricted intention signaling, low emotional/physiological arousal, and decreased glucocorticoid production

  • When behavior ratings are derived from observers, positive relationships between testosterone and dominance or aggression are consistently observable. These and many other findings document that, high levels of testosterone promote the pursuit of dominance and status in socially acceptable ways, but in some cases they can lead to aggression, antisocial behavior and this type of behavior we propose to label as the Strauss-Kahn syndrome (SKS)

  • The association between times of psychologic distress and reductions in proliferative response of lymphocytes cultured with mitogens, are mitogens that activate T-cells. This in vitro measure of lymphocytes activation, sensitive to psychosocial influences is linked to any disease outcome

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Summary

Introduction

Unemotional violence associated with aggression stress is often called ‘predatory’ because it involves a restricted intention signaling, low emotional/physiological arousal, and decreased glucocorticoid production. Authoritarian personality, aggression and dominance N Power is positively correlated with baseline testosterone, suggesting that high baseline levels of testosterone manifest an authoritarian individual’s personality. N Power positively predicts mane of the dominance behaviors that high levels of testosterone are associated with: entering influential occupations, drug abuse, spousal abuse, risk taking, and sexual promiscuity.

Results
Conclusion

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