Abstract

The effect of an aqueous leaf of Ageratum conyzoides on gastric acid secretion in rats was investigated in 18 albino rats of Wistar strain. The rats were divided into 2 groups of 9 each. Gastric acid output was determined by continuous perfusion in urethane anaesthetized rats. Control gastric acid output was obtained usign 0.9% NaCl as perfusate, and extract-induced gastric output was obtained by perfusion with a 0.1% solution of A. conyzoides. Intragastric administration of the extract caused significant increase in the mean gastric acid output (p

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