The steady motion of microbubbles in bifurcating airways: Role of shear-thinning and surface tension

Abstract

Mucous fluid is non-Newtonian secretions in the lower lung airways that accumulates when the alveolar-capillary membrane ruptures during acute respiratory distress syndrome. The mucus fluid has, therefore, different types of non-Newtonian properties like shear-thinning, viscoelasticity, and non-zero yield stress. In this paper, we numerically solved the steady Stokes equations along with arbitrary Eulerian-Lagrangian moving mesh techniques to study the microbubble propagation in a two-dimensional asymmetric bifurcating airway filled with non-Newtonian fluid where the fluid has shear-thinning behavior described by the power-law model. Numerical results show that both shear-thinning and surface tension characterized by the behavior index (n) and Capillary number (Ca), respectively, had a significant impact on microbubble flow patterns and the magnitude of the pressure gradient. At low values of both n and Ca, the microbubble leaves a thin film-thickness with the airway wall while a large and sharp peak of the pressure gradient near the thin bubble tip. Interestingly, increasing both n and Ca, leads to an increase in film thickness and a decrease in the pressure gradient magnitude in both the daughter airway walls. It is observed the magnitude of the pressure gradient is more sensitive to Ca compared to n. We concluded that shear-thinning and surface tension not only significantly impact the patterns of microbubble propagation but also the hydrodynamic stress magnitudes at the airway wall.