Abstract

Vivax malaria caused by Plasmodium vivax (Pv) is one type of parasitic diseases seriously endangering human health, it recently becomes a hotspot to control this parasite by use of the vaccine. Pv merozoite surface protein 1, Pv circumsporozoite protein, Pv apical membrane antigen 1 and Pvs25 antigens are many types of candidate vaccine molecules. This review outlines the status in the research of vaccine of Plasmodium vivax mediated by bacteria such as Mycobacteria smegmatis, Agrobacterium tumefacies, and Pichia pastoris, and by viruses such as Adenovirus and Baculovirus. Key words: Plasmodium vivax; Antigen; Vaccine; Review

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