Abstract
Normal and senile cataractous lenses were studied by nuclear magnetic resonance in order to get information about the state of water during the progression of cataract. Water proton spin-spin ( T 2) and spin-lattice relaxation times—in the laboratory and the rotating frame—( T 1 and T 1 o ̧ ) were measured at 34 and 90 MHz. At temperatures below −9°C the relaxation times of protons in “non-freezable” component of lens water were measured as a function of the temperature, and T 1 and T 2 relaxation times were found to be the same for both the normal and the cataractous lenses. At temperatures above −9°C a marked difference in relaxation times T 1 and T 2 was found between normal and completely opaque lenses. It was concluded that the most characteristic difference between the normal and completely opaque lenses should be accounted for by the change in the “bound”-to-“free” ratio of lens water.
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