The state of the structure of the cerebral cortex at various times of the postmortem period after massive blood loss complicated by hemorrhagic shock

Abstract

The aim of this study is to reveal the features of changes in the structure of the cerebral cortex at different periods of the postmortem period after death from massive blood loss complicated by hemorrhagic shock. The morphological and morphometric features of the nervous and vascular structures were determined during death from blood loss complicated by hemorrhagic shock. The brain of 12 corpses of persons who died from stab and cut wounds of blood vessels and internal organs with sharp instruments at various times of the postmortem period were examined. It was found that as the time elapsed after death from hemorrhagic shock increases, an increase in destructive changes in both neurons and intracerebral vessels is observed in the brain. Autolytic processes to a greater extent occur in the intracerebral vessels in comparison with neurons, which is more pronounced in the later periods. The dimensions of the perineuronal and perivascular spaces in the dynamics of the postmortem period increase synchronously after death from hemorrhagic shock.