Abstract

The state of intranasal structures was compared in patients with EOM and AR and EOM without AR. It was determined that the most likely cause of the violation of the protective function of the nasal mucosa in patients with EOM and AR is serous inflammation, manifested by a number of structural and functional changes. Structural changes are characterized by de-epithelialization of the mucous membrane in the acute phase, an increase in the number of goblet cells, a change in the viscosity of the medium, and a change in the pH of the medium. Each of the described processes ultimately leads to a slowdown in mucociliary transport, which occurs in the patients with EOM and AR that we examined. Thus, the curvature of the nasal septum and other features of the architectonics of intranasal structures in patients with EOM to a lesser extent than in patients with EOM and AR affect the development of the disease.

Highlights

  • The prevalence of exudative otitis media (EOM) is especially high among children: according to some foreign authors, the disease occurs in 5-25% [1,2,6], and others - in 6.5 to 10.9% [4]

  • The curvature of the nasal septum and other features of the architectonics of the intranasal structures in patients with EOM to a lesser extent than in patients with EOM and allergic rhinitis (AR) affect the development of the disease

  • The results of a comparative analysis of the history and rhinoscopy data clearly demonstrate the dependence of relapses of exudative otitis media on the state of intranasal structures in patients of group 1 and the absence of such in patients of group 2

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Summary

Introduction

The prevalence of exudative otitis media (EOM) is especially high among children: according to some foreign authors, the disease occurs in 5-25% [1,2,6], and others - in 6.5 to 10.9% [4]. This indicator reaches its maximum values at the age of 2-5 years, and by the age of 10, 80 children have a history of at least one episode of EOM [3]. The high frequency of EOM in children - 4 times more often than in adults - is associated with anatomical prerequisites: a short horizontal auditory tube contributes to infection of the middle ear cavity [8,9,10]

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