Abstract

The problem of the long-term effects of COVID-19, especially its severe forms, is already acutely relevant for world healthcare. Severe course of the novel coronavirus infection (cytokine storm) may be accompanied with the damage of respiratory system, circulatory system, and hemostasis.
 In the Department of Hospital Therapy Military Medical Academy have been examined 64 servicemen: 1st group of 44 people aged 46.1 7 years with developed cytokine storm; 2nd group 20 men 47 4.4 years without this complication. Patients were screened and treated under the standard scheme; 3 months after discharge from the hospital, respiratory, heart failure and D-dimer levels were assessed.
 There was a significant increase pulmonary damage with decrease in saturation to 92.3 % (p = 0.003) in the 1st group; laboratory signs of myocardial lesions: increase of troponin T to 15.4 ng/l (p = 0.001), a significant increase in the total creatine phosphokinase, aspartate amine transferase and alanine aminotransferase compared to patients of the 2nd group. The average rates of standard hemogram, with the exception of platelet levels (173 103/l, p = 0.03) in the 1st group were no different from similar parameters of patients from the 2nd group. It was drawn to attention the reliable increase in C-reactive protein, D-dimer and ferritin in men of the 1st group. During the reexamination after 3 months more often diagnosed the phenomenon of respiratory and heart failure and hypercoagulation in patients from the 1st group, which dictates the need for further dynamic monitoring of this category (1 figure, 2 tables, bibliography: 14 refs).

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