Abstract

 
 
 
 Aim: to study the state of local immunity and oral hygiene in patients with GP suffering from AN.Materials and methods: 35 patients with AN were examined at the age of 19-35 years. In the study we used immunological methods, an index assessment of the state of oral hygiene (PMA, API, GI).Results and discussion: in patients of I group poor oral hygiene was established. The amount of lysozyme in the oral fluid in I group was 0.014 ± 0.07 g/l. A decrease SIgA (11SIgA) was established in patients of I group: I, II and control (135.31 ± 23.17, 130.26 ± 24.21 and 300.34 ± 27.38 mg/l, respectively). A tendency to an increase in the level of IgG in the oral fluid in patients of group II compared with I and the control group (5.35 ± 0.36, vs. 4.57 ± 0.04 and 4.98 ± 0.23 g/l, respectively) was established.Conclusions: poor oral hygiene is an objective indicator which reflects low motivation to maintain oral health. The observed immunodeficiency (11SIgA) in patients with GP is a mirror image of changes occurring in the body of patients with AN.
 
 
 
Highlights
Diseases of periodontal tissues, including generalized periodontitis (GP), occupy one of the key positions in the structure of dental diseases [3]
Poor oral hygiene according to indicative hygienic indicators (RMA, API, GI) in all patients with GP initial-І degree of chronic course, burdened with AN, could indicate that the aggressiveness of periodontal microorganisms contributes to aggravation and acceleration of the pathological process periodontal tissues, and serves as a potentiating component supporting and aggravating the course of anorexia nervosa
The unsatisfactory state of oral hygiene serves as an objective indicator reflecting low motivational components to maintaining oral health, as well as showing a lack of an objective understanding of the risks to their overall health
Summary
Diseases of periodontal tissues, including generalized periodontitis (GP), occupy one of the key positions in the structure of dental diseases [3]. In recent years, their prevalence has increased significantly and, according to a number of researchers, has reached 57-80%. Androgens and estrogens, which regulate protein-calcium metabolism, are considered to be one of the leading factors influencing bone tissue remodeling processes. The level of the latter undergoes significant changes in a number of conditions and diseases, including, anorexia nervosa (AN)
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