The standard development of nanoparticle exposure assessment through SP/ICPMS equipment

Abstract

The development of nanotechnology, particularly of nanoparticles, is having a revolutionary effect in science and technology. Accordingly, it receives unexpected adverse effects (e.g. ecotoxicological) which can be caused by the special properties of the nanoparticles. [1], [2] It is important to develop with suitable physical and chemical properties of nanoparticles. So there is requiring a study on the safety and the risk of the nanoparticles as well as the development of nanotechnology.In this work, the size and size distributions of liquid suspension containing well-dispersed standard nanoparticles are measured by single particle inductively coupled plasma-mass spectrometry (SP/ICPMS). The advent of SP/ICPMS has helped advance the field of nanometrology, specifically at concentrations and in matrices that are environmentally relevant. SP/ICPMS is a technology that can be applied to metal nanoparticle analysis of 20 nm or more. The required concentration in the sample has the advantage that it can be analyzed sufficiently below the ppt level. The size distribution measurements of nanoparticles are made using NIST Gold Standard Reference Materials (SRM). These were compared with certificate values. And we have found reliable measurement conditions through repeated measurement. Thereafter, the results were compared the size measured by transmission electron microscopy (TEM) and scanning mobility particle sizer (SMPS).