THE STABILITY STUDY OF GINGER EXHAUSTIVE EXTRACTION USING HPLC

Abstract

Ginger contains biologically active components that may contribute significantly to the therapeutic applications of ginger and some ginger-derived products. 6-Gingerol has long been used as a ginger marker. HPLC was used to perform quantitative measurements of 6-Gingerol and its principal degradation product. In addition, the pH factor to be one of the most important factors in the stability condition of ginger liquid extractions. The rate of degradation was shown to be pH dependent, with the maximum stability at pH 4. At 100°C and pH 1, the reversible breakdown of 6-gingerol was quite quick, reaching equilibrium in less than 2 hours. The coefficient of correlation were larger than 0.994. The HPLC approach described in this article has been validated by researchers and can be used to verify the stability of 6-gingerol. It is also suitable for ginger reformulation research. The stability of ginger solution at various pH (4-7) was investigated. The content of 6-gingerol in various formulations was assessed. Ginger stability: According to the regulations, the extract must be stable after 180 days at 40 degrees Celsius, with not more than 10% of the active component or active markers degraded. Therefore, the experimental work has been put on hold while the researchers wait for the samples to go through the process of repose at 40 degrees Celsius for a period of time, after which they will be analyzed; if the results are promising, the researchers will continue to confirm the final time of 180 days; if not, the researchers will try another theory.