Abstract

Introduction: Cervical carcinoma is one of the leading causes of death among women worldwide. An estimated of 2,30,000 women die annually from cervical cancer, and almost 1,90,000 are from developing countries. It is considered to be the 3rd most common malignancy among women. Materials and Methods: This is a 5 year retrospective study done in the department of pathology, Kasturba medical college, Manipal. Hysterectomy and cervical biopsies are included in this study. Clinical details were obtained from case sheets. Results: 175 cases of cervical neoplasms were studied in total. The patient’s age was ranged 21 to 80 years with mean being 50.5 years. Among the commonest complaints was post-menopausal bleeding followed by menorrhagia and intermenstrual spotting. 49% cases had a growth in the cervix followed by 12% cases with induration and 10% cases as polyp in cervix. Among the 175 cases, 14.86% cases were precursor lesions. Among the malignant cases, squamous cell carcinomas (61.71%) were the commonest. Rare tumour includes 2.86% cases of minimally invasive carcinoma, 1.71% cases of neuroendocrine carcinoma, and 1.14% cases each of serous carcinoma. Conclusion: Neoplastic lesions from the uterine cervix comprise of a wide variety of lesions originating from both the epithelial and stromal elements. Among the malignant tumours, squamous cell carcinoma was very common. Hence, a thorough clinical evaluation and post-menopausal health check-ups along with detailed cervical examination and microscopic evaluation is the key towards correct and timely diagnosis of cervical neoplasms.

Highlights

  • Cervical carcinoma is one of the leading causes of death among women worldwide

  • The remaining tumors were adenobasaloid carcinoma, lymphoepithelial like carcinoma, carcinosarcoma and colloid carcinoma accounting for one case each. (Table 1)

  • World health organization reports that cervical carcinoma has an estimated 570,000 new cases in 2018 representing 6.6% of all female cancers [7]

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Summary

Introduction

An estimated of 2,30,000 women die annually from cervical cancer, and almost 1,90,000 are from developing countries. Results: 175 cases of cervical neoplasms were studied in total. Squamous cell carcinomas (61.71%) were the commonest. A thorough clinical evaluation and post-menopausal health check-ups along with detailed cervical examination and microscopic evaluation is the key towards correct and timely diagnosis of cervical neoplasms. Uterine cervix carcinoma is the 3rd most common cancer among females worldwide, next to breast and lung carcinoma. Studies have shown that more than 80% of patients dying of cervical carcinoma are from developing countries [1]. In South India, carcinoma cervix is the most common form of cancer in females [1,3]. The disease is more prevalent in people living in poor living conditions and low-income groups, probably because of lack of hygiene and lack of regular health check-up due to financial constraints

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