Abstract
1. The thermolability of the specific polysaccharides of Types I, II, and III pneumococcus has been shown by three independent methods: (a) diminution of the viscosity of solutions on heating; (b) decrease in the amount of antibody precipitated from homologous rabbit antisera; and (c) increased tendency (S III) to pass through a collodion membrane. 2. These effects may be explained most simply as a partial depolymerization under the influence of heat. In air, particularly in the presence of broth, oxidation also appears to be involved. 3. Improved and simpler methods of preparation based on these findings, are given for S I, S II, and S III. The resulting products precipitate more anti-S from homologous rabbit antisera than do the earlier preparations. 4. The methyl glycoside of methyl galacturonate has been isolated from the hydrolytic products of S I, and evidence of the ultimate structural unit obtained.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.