The specific features of central nervous system lesions in children with type 1 diabetes mellitus

Abstract

The specific features of central nervous system lesions were studied in 100 children with type 1 diabetes mellitus (DM), by using the data of a survey, rheoencephalography (REG) and psychological tests (cognitive and emotional processes). The cerebroasthenic syndrome that manifested itself as headache (42%), dizziness (33%), overfatigability and weakness (49%) was diagnosed by the analysis of complaints. REG established that 42% of the children with DM have cerebral circulatory disorders. Psychological tests revealed cognitive disturbances in 74 children with DM, of them 54, 59, 21, and 30 children diminished thinking, mechanical and logical memory, and attention, respectively. Fifty children were found to have emotional disorders as anxiety in 50 children, depression in 32, and aggression in 25. The psychoneurological syndrome in the presence of DM was diagnosed in 33%; it appeared mainly as behavioral deviations (hypersexuality, autism, theft, and falseness). The level of cerebral circulation and cognitive and emotional processes in the examinees correlated with the values of HbA1с. Impairments of cerebral hemodynamics, cognitive and emotional' sphere were encountered in decompensated carbohydrate metabolism more frequently than in compensated and subcompensated DM (p < 0.01 and p < 0.05).