Abstract
The present study investigated the association of 3'-UTR VNTR and intron 8 VNTR polymorphisms with a time estimation task performance. One hundred and eight men in a Brazilian Northeast population (18-32years old) participated in the experiment. The 3'-UTR VNTR and intron 8 VNTR polymorphisms were associated alone and combined to absolute error (AE) and relative error (RE) in a time estimation task (target duration: 1s, 4s, 7s and 9s). We found an association of the behavioral variable with intron 8 VNTR for the time intervals of 1s and 9s (p < 0.001) and polymorphisms combinatorial effect for 1s (p ≤ 0.05). The intron 8 VNTR polymorphism and the combinatorial effect can modulate the time estimate in the domain of supra seconds, and thus our study indicates a role of the dopamine transporter in the neurobiological areas related to the time intervals judgment.
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