Abstract

In the kids' cartoon, slacker Shaggy and his canine sidekick Scooby Doo snarfed Scooby Snacks that, according to urban lore, contained a magic ingredient: marijuana. Maybe that's why Shaggy had bad posture. New results reveal that activating a marijuana receptor spurs bone loss, and obstructing it reinforces bone, at least in mice. If the findings hold up in people, receptor-blocking drugs--already in trials to battle obesity--might combat osteoporosis.

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