The size of serum hepatitis virus.

Abstract

Summary1. Known icterogenic (SH) serum (J.W. strain), undiluted and diluted 10% in normal saline, was filtered through gradocol membranes of various average pore diameters down to 52 mμ, and tested in human volunteers. 2. Evidence has been presented that the strain of serum hepatitis virus used is small enough to pass through a 52 mμ A.P.D. membrane, thus indicating a size of 26 mμ or less. The limitations of the application of this method for determining the size of this virus are mentioned.The author is indebted to Dr. John R. Paul for valuable advice and criticism.