Abstract
IN A previous publication (Purves and Griesbach, 1951) the presence of two distinct kinds of basophil cells in the anterior pituitary of the rat was reported. Evidence was presented that one of these kinds was exclusively concerned with the production of thyrotrophic hormone, while the other was exclusively gonadotrophic in function. It was considered that the latter cells were responsible for the secretion of the follicle stimulating hormone, but the observations made at the time were inadequate to establish the site of production of the luteinising hormone. More recent observations have shown that the gonadotrophic basophils of the rat pituitary may be further subdivided into two specific types. One type has a peripheral distribution in the anterior lobe, and under most circumstances, gives a strong glycoprotein reaction with the periodic acid-Schiff procedure for the demonstration of glycoprotein. In the interior of the anterior lobe
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