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Abstract
1. The addition of rat chylomicra to plasma from which the particulate fat has been removed by high‐speed centrifugation greatly increases the amount of thrombin formed in a thrombin generation test.2. Several brain ethanolamine phosphatide preparations also markedly increase the amount of thrombin generated in similar tests. Serine phosphatide, inositol phosphatide and lecithin are inactive.3. Acid hydrolysates of chyle contain a substance resembling ethanolamine in its ionophoretic and chromatographic behaviour. Also present are substances resembling choline and serine.4. It is concluded that ethanolamine phosphatide is probably the phosphatide component of the chylomicron which is active in the coagulation tests.
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