Abstract
Aim: to determine the relationship between of levels»protoxic» metabolites and «profibrotic» metabolites in the blood serum in children with chronic viral hepatitis C (HCV).Material and methods: the authors examined 54 children 14.0[6,0] years old with HCV. The blood serum levels of Molecules of average mass, Oligopeptides, Alcohol dehydrogenase, Glutathione-S-transferase, Ammonia, Arginase and Collagen IV have been studied.Results: A high level of «protoxic» metabolites in the blood serum was associated with a disorder of their elimination. The relationship with viral replication and biochemical hepatitis activity has not been identified. The collagen IV blood serum level was correlated with the accumulation and elimination of «protoxic» metabolites: R = 0.63, F = 5.19, p = 0.018.Conclusion: The level of collagen IV in the children's blood serum was associated with the accumulation and the elimination of «protoxic» metabolites.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
