Abstract

The development of embryonic blood was studied in pig embryos from 15mm. in length on through the fetal stages. The formation of blood plastids by budding and pinching off has been confirmed at least for the primitive stages. The blood platelets of the primitive stages (15 to 35 mm.) resemble the cytoplasm of the primitive erythroblasts or haemocytoblasts. The more primitive cells of the erythrocyte series (haemocytoblasts) contain a reticular substance in their cytoplasm before there is any evidence of oxyhemoglobin. The nucleus of these primitive red cells does not take the supravital dye, but the pyknotic nucleus of the megalocytes and normoblasts stains intensely by the supravital, technique. A karyolysis of the senile red cells of the first family (megalocyte series) has been confirmed.

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