THE SIGNIFICANCE OF JOINT PAINS CAUSED BY STERILE STREPTOCOCCUS TOXIN

Abstract

Article1 July 1943THE SIGNIFICANCE OF JOINT PAINS CAUSED BY STERILE STREPTOCOCCUS TOXINPAUL S. RHOADS, M.D., F.A.C.P., MELVIN L. AFREMOW, M.D.PAUL S. RHOADS, M.D., F.A.C.P.Search for more papers by this author, MELVIN L. AFREMOW, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-19-1-60 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1937 Healey1reported that about 3 per cent of young adults being immunized against scarlet fever developed multiple joint pains as a reaction to one or more injections of the sterile filtrate of broth cultures of scarlet fever streptococci. She noted that the majority of persons who had this reaction gave a history of previous joint pains associated with rheumatic fever, or of streptococcus infections of the nose and throat. We had made similar observations. Healey showed that 74.6 per cent of a group of 63 such persons which she studied did not have joint pains when injected with...Bibliography1. HEALEY CE: The cause of joint pain occurring during immunization with scarlet fever streptococcus toxin, Jr. Am. Med. Assoc., 1937, cviii, 628. CrossrefGoogle Scholar2. COBURNPAULI AFRH: Studies in the immune response of the rheumatic subject and its relationship to activity of the rheumatic process. IV. Characteristics of strains of hemolytic streptococci effective and non-effective in initiating rheumatic activity, Jr. Clin. Invest., 1935, xiv, 766. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Evanston, Illinois*Delivered before the Regional Meeting of the American College of Physicians, Chicago, Ill., November 21, 1942.From the Department of Medicine, Northwestern University Medical School, and the Nurses' Infirmary of Cook County Hospital, Chicago. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe allergist's stake in collagen diseaseSerum electrophoretic pattern in experimental hypersensitivityRole of Dental Focal Infection in Etiology of DermatosisExperimental collagen disease from hypersensitization to streptococcus toxinThe Ætiology of Chronic RheumatismActive Immunization 1 July 1943Volume 19, Issue 1Page: 60-63KeywordsArthralgiaGroup A streptococciHospital medicinePharynxRheumatic feverScarlet feverStreptococcal infectionsStreptococcusToxinsYoung adults ePublished: 1 December 2008 Issue Published: 1 July 1943 PDF downloadLoading ...