Abstract
Objective: To determine if there is any significant association between stroke and both hypoalbuminema and hypoproteinemia. Patients and Methods: Total serum proteins “T.S.P.” and serum albumin were measured for 65 patients with stroke who were admitted to the medical and neurological wards at Baghdad Teaching Hospital in the Medical City from November 2003 to October 2004. Careful history was obtained and proper clinical examinations were done. Serum albumin, T.S.P., blood sugar, renal function, liver function and general urine examination “G.U.E.” were tested within 48 - 72 hours of the start of patient symptoms. These patients with hepatic and renal dysfunction and those with diabetes mellitus were excluded. The results were compared with the results obtained from control group, which consisted of 40 persons of matched age and sex. By application pf chi square test “X” to see the association of serum albumin with cigarette smoking, age, hypertension and the presence of carotid bruit. Results: The mean serum level of T.S.P. and serum albumin of those with stroke was 6.42 ± 0.322 g/dl, 3.26 ± 0.251 g/dl respectively, which was significantly lower than T.S.P. and serum albumin of the control “mean = 7.8 ± 0.257 g/dl, 4.73 ± 0.206 g/dl respectively” [P X2 = 25.14, P X2 = 15.57, P < 0.025] and the blood pressure with serum albumin P < 0.0005, and the presence of carotid bruit is associated with low level of albumin P < 0.005 “Fisher’s test”. Conclusion: Hypoalbuminemia and hypoproteinemia are significantly associated with stroke.
Highlights
Atherosclerosis is an arterial disease that is recognized to be the chief cause of death in the world [1].The role of atherosclerosis as a principal cause of myocardial infarction and thrombosis has been appreciated for many years
This study reveals that there is an inverse relationship between the age [X2 = 25.14, P < 0.005], number of cigarettes [X2 = 15.57, P < 0.025] and the blood pressure with serum albumin P < 0.0005, and the presence of carotid bruit is associated with low level of albumin P < 0.005 “Fisher’s test”
Hypoalbuminemia and hypoproteinemia are significantly associated with stroke
Summary
Atherosclerosis is an arterial disease that is recognized to be the chief cause of death in the world [1].The role of atherosclerosis as a principal cause of myocardial infarction and thrombosis has been appreciated for many years. Atherosclerosis is an arterial disease that is recognized to be the chief cause of death in the world [1]. A major problem is that the disease progresses insidiously for many years before symptoms develop making it difficult to follow the early development of the disease in individual patients, and to relate causally the several types of lesions that have been described [3]. Identification of the risk factors is to the clinical symptoms rather than on the extent and severity of primary arterial lesion. Not surprisingly many researches in area of atherosclerosis had individual thesis risk factors [4] [5] [6] especially hyperlipidaemia [7] [8] [9] and hypertension [10]
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