Abstract

Aim. To evaluate the effectiveness of extracorporeal hemocorrection during a various spectrum of therapeutic diseases. Methods. To date we have conducted more than 10,000 operations of extracorporeal hemocorrection. The most widely used for therapeutic diseases was hemodialysis: during end-stage chronic kidney disease, temporary renal failure, caused by exacerbation of the underlying disease, poisoning with dialysing toxins, severe disorders of electrolyte composition of the blood, fluid overload with the development of pulmonary edema, severe endotoxemia. Results. Plasmapheresis played a major role in the treatment of somatic patients with dyslipidemia, obstructive jaundice, destructive pancreatitis, septic processes, liver failure and poisoning. Extracorporeal ultraviolet irradiation of blood was used mainly for pneumonia, gastric and duodenal ulcers, hyperthyroidism, viral hepatitis, neural infections, pyelonephritis, acute pancreatitis, burn disease, acute and chronic pyo-inflammatory processes of various locations. We have identified many disadvantages and complications during the usage of hemosorption and this narrowed down the indications of this method hemocorrection and detoxification. We believe the contraindications for hemodialysis to be cancers, uncontrolled arterial hypotension, ongoing internal bleeding; for the plasmapheresis - terminal condition of the patient, the lack of vascular access, uncontrolled arterial hypotension. Conclusion. The experience of extracorporeal hemocorrection gained in the clinics of Samara Military Medical Institute and continued within the setting of a hospital, requires further detailed investigation. Improvement of the above mentioned methods we assume to lead in the direction of their combined use.

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