Abstract
Periungual fibroma is a diagnostic criterion of tuberous sclerosis (TS), with generally no consideration given to the number of fibromas or their location.<sup>1-3</sup>Recently, Roach et al<sup>4</sup>and Kwiakowski and Short<sup>5</sup>stated that periungual fibromas are a significant criterion of TS if there are many fibromas. However, clinical studies confirming this assertion are lacking. Therefore, we examined whether the usual tests performed to rule out TS are necessary in patients presenting with a periungual fibroma.<b>For editorial comment see page 1460</b> <h3>Patients and Methods.</h3> Seven consecutive patients, 30 to 53 years of age, were seen between 1989 and 1993 for solitary periungual fibroma. All tumors were excised and examined histologically. A thorough evaluation was performed in each case, including extensive inquiry of personal or familial events suggestive of TS, physical examination (including Wood's light), and laboratory investigations to detect the occult signs of TS. Furthermore, we reviewed
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
