Abstract
Objective: In last years it becomes more and more evident that focal EEG changes can be detected in patients with idiopathic generalized epilepsies. In order to estimate the frequency of this changes and their possible prognostic value present study was undertaken. Methods: Patients with typical absence seizures who were hospitalized or consulted at Dept. of Developmental Neurology between 2000–2015 were included in the study and followed prospectively. All patients underwent video-EEG monitoring at regular intervals. 189 patients who fulfilled criteria for typical absence seizures were included in the study. In 17% of them we found interictal epileptiform discharges, and in 37% intermittent temporal slow waves. Results: We found significant correlation between presence of interictal focal epileptiform discharges and long term prognosis, but did not find the correlation between worse prognosis and presence of temporal interictal slow wave activity. Interestingly, we did not found correlation between presence of focal abnormalities and worse performance in cognitive tests. Conclusion: The value of focal interictal EEG abnormalities should not be overestimated according to prognosis and cognitive performance in children with CAE.
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