Abstract
On the basis of measurements on fresh human brains ( n=33), changes in size of the brain stem which occurred as a result of formalin fixation and embedding in paraffin were quantified and converted into linear correction factors. In contrast to the known changes in the cerebrum, the formalin fixation did not result in a `positive formalin effect', but left transverse values unchanged and led to decreases in longitudinal distances of 1–8% (correction factors: 1.01–1.09). Further embedding resulted in a linear shrinkage of 11–12% (correction factors: 1.12–1.13) transversely and 17% (correction factor: 1.21) longitudinally, which was smaller than the shrinkage in the cerebrum of 11–25% (correction factors: 1.13–1.34) reported in the literature. The examinations revealed changes in the brain stem caused by the total fixation and embedding process different from those of the cerebrum.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.