The Short Physical Performance Battery Score Is Associated With Quality Of Life In Black And Hispanic Outpatients With Stable Congestive Heart Failure

Abstract

Introduction Functional status is associated with poor health outcomes, including quality of life. The Short Physical Performance Battery (SPPB) is commonly used to assess functional status. However, there are limited data describing quantifiable functional status limitations in Black and Hispanic patients with stable congestive heart failure. We hypothesized that in a Black and Hispanic outpatient population with heart failure, low functional capacity, as determined by low SPPB score, would be associated with worse quality of life. Methods The multicenter, prospective, Screening for Cardiac Amyloidosis in Minority Populations (SCAN-MP) study identified Black and Hispanic subjects with heart failure, collected baseline characteristics, and measured SPPB. Quality of life was measured by the Kansas City Cardiomyopathy Questionnaire (KCCQ). SPPB scores were stratified into severe functional deficit (0-6), mild functional deficit (7-9) and no functional deficit (10-12). Results Of 220 patients in the study, 201 (91.3%) completed the SPPB. SPPB score was associated with the overall KCCQ score and with multiple subdomains of the KCCQ, but not exclusively with physical limitation (Table 1). Patients with low SPPB scores were more likely to be older, female, have higher BMI and NYHA class, less education, more comorbidities, and worse Six-Minute Walk Test (Table 2). Conclusion Among Black and Hispanic outpatients with stable heart failure, stepwise decrements in functional status, as defined by the SPPB, are associated with overall KCCQ score, and scores across a variety of sub-domains. These findings suggest that targeted interventions to improve patients’ functional status could broadly benefit quality of life. Functional status is associated with poor health outcomes, including quality of life. The Short Physical Performance Battery (SPPB) is commonly used to assess functional status. However, there are limited data describing quantifiable functional status limitations in Black and Hispanic patients with stable congestive heart failure. We hypothesized that in a Black and Hispanic outpatient population with heart failure, low functional capacity, as determined by low SPPB score, would be associated with worse quality of life. The multicenter, prospective, Screening for Cardiac Amyloidosis in Minority Populations (SCAN-MP) study identified Black and Hispanic subjects with heart failure, collected baseline characteristics, and measured SPPB. Quality of life was measured by the Kansas City Cardiomyopathy Questionnaire (KCCQ). SPPB scores were stratified into severe functional deficit (0-6), mild functional deficit (7-9) and no functional deficit (10-12). Of 220 patients in the study, 201 (91.3%) completed the SPPB. SPPB score was associated with the overall KCCQ score and with multiple subdomains of the KCCQ, but not exclusively with physical limitation (Table 1). Patients with low SPPB scores were more likely to be older, female, have higher BMI and NYHA class, less education, more comorbidities, and worse Six-Minute Walk Test (Table 2). Among Black and Hispanic outpatients with stable heart failure, stepwise decrements in functional status, as defined by the SPPB, are associated with overall KCCQ score, and scores across a variety of sub-domains. These findings suggest that targeted interventions to improve patients’ functional status could broadly benefit quality of life.