Abstract

An inquiry was made into the activity of the glutamico-asparagic and glutamico-alanine transaminase in the blood serum of rats and dogs at various periods after the administration of carbon tetrachloride. The maximal rise of the transaminases activity in the blood serum of rats was observed in 24 hours after a single administration of CCl4; the ratio of the activities of glutamico-asparagic and glutamico-alanine transaminase was below 1. Considerable rise of the transaminase activity in the blood serum of rats was observed after 15 times administration of CCl4 given every other day. However, the ratio of the glutamicoaspargic transaminase and glutamico-alanine transaminase ratio was over 1.

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