Abstract

Serum insulin and human growth hormone (HGH) levels were measured in 33 premature infants during the first 24 hours of life, following the infusion of arginine, glucose, and glucose plus arginine. Infusion of arginine (2.5 g) was followed by a moderate early rise in serum insulin and a marked and delayed rise in serum HGH. Glucose (1.25 g) infusion resulted in a small insulin response and a rise of serum HGH. However the simultaneous administration of arginine and glucose, each in amounts of 1.25 g, was associated with a prompt marked rise of serum insulin and a delayed rise of serum HGH.

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