The selenium accumulation and its effect on growth, and haematological parameters in red sea bream, Pagrus major, exposed to waterborne selenium

Abstract

Juvenile Pagrus major (mean length 15.8±1.6cm, and mean weight 90.4±4.7g) were exposed for 4 weeks with waterborne selenium concentration (0, 50, 100, 200, and 400µg/L). The profile of Se accumulation among tissue in P. major is dependent on the exposure periods and Se concentration. After 4 weeks, the highest accumulation of Se was observed in the kidney, and the order of Se accumulation in tissues was kidney≈liver>spleen>intestine>gill>muscle. Se decreased the growth rate, and there was an inverse proportion between growth and Se concentration. The major hematological findings were significant decrease in the RBC count, Ht value, and Hb concentration exposed to ≥100µg/L Se concentrations. Se exposure (≥100µg/L) led to significant increase in the glucose, GOT, and GPT levels, whereas the levels of calcium, magnesium, cholesterol, and total protein did not increase. The results suggest that waterborne Se exposure can induce significant Se accumulation in tissues, inhibition of growth, and hematological alterations.