The sedative efficacy of nasal dexmedetomidine used for premedication in ocular trauma children undergoing emergency surgery

Abstract

Objective To evaluate the efficacy of optic canal decompression for traumatic optic neuropathy, and analyse the effect of flash visual evoked potential (F-VEP) on early diagnosis and evaluation of surgical efficacy in traumatic optic neuropathy. Methods The data of 40 eyes of 40 patients with traumatic optic neuropathy from Jun. 2010 to May 2017 were retrospectively analysed. They were randomly divided into 2 groups. The observation group, 17 cases were treated with optical canal decompression through transsphenoidal approach under neuroendoscopye. The control group, 23 cases were treated with craniooptic canal decompression. The visual acuity and P2 wave latency changes of F-VEP were examined before surgery, 10 days and 3 months after surgery. The follow-up time was 3 months after surgery. Results The difference of the age, gender, Glasgow Coma Scale, visual acuity, duration trauma to surgery and P2 wave latency than the healthy eye before surgery were not statistically significant between the two groups (P>0.05). The effective rate in observation group at 10 days after surgery was 82.35%, and 69.56% of the control group. The total effective rate of the observation group at 3 months after surgery was 82.35%, and 78.26% of the control group. The difference was not significant between the two groups (P>0.05). Visual acuity was significantly correlated with the prolongation of P2 wave latency in the corresponding F-VEP at 10 days and 3 months after operation. Conclusion It is a significant correlation between P2 wave latency in F-VEP and visual acuity. Endoscopic transnasal optic canal decompression is an effective method for the treatment of traumatic optic neuropathy. Key words: Neuropathy, optic, traumatic; Decompression, canal, optic; Evoked potential, visual, flash