The screening and monitoring of type 2 diabetes by indirect calorimetry

Abstract

An increasing amount of study is being dedicated to the identification of biomarkers associated with type 2 diabetes, with particular emphasis on the field of Metabonomics. To screen and prevent type 2 diabetes, indirect calorimetry measures real-time oxygen consumption (V_02) and carbon dioxide production (V_C02) and measures an individuals metabolic tendency which is the ratio of glucose and fat as energy substrate for a specific activity. A person with aberrant glucose metabolism after measurement may have type 2 diabetes. Adjusting food intake helps type 2 diabetics control blood glucose. Now, type 2 diabetes become personalized. In other words, type 2 diabetes needs to be analysed case by case. The population can be divided into different categories in terms of metabolic adjustment. After classification, indirect calorimetry can be used in clinical research whose purposes are to screen, prevent and treat type 2 diabetes. This paper uses literature reviews to summarize the genetic factors and environmental factors of type 2 diabetes, explain the necessity and limitations for screening, monitoring, preventing and curing type 2 diabetes, and the reasons for calorimetry can screen and monitor type 2 diabetes and how to calculate the percentage of energy substrates for a certain activity.