Abstract
The purpose of the work – to analyze data of modern scientific literature regarding thedetermination of the role of Schwann cells in the regeneration of the peripheral nerve.Conclusions. 1. Dysfunction of Schwann cells is an important factor in the delay, and insome cases, the absence of recovery of function after peripheral nerve injuries. 2. Moderntreatment should be aimed at activating the repair program in Schwann cells, initiatingthe recruitment of macrophages, stimulating the synthesis of neurotrophic factors byneuroleumocytes and macrophages, optimizing metabolism and the immune response incase of traumatic damage to main nerve trunks. 3. The use of genetic engineering toinfluence the genes that regulate the activity of Schwann cells during injuries may bea promising strategy in the treatment of this nosology. 4. The regenerative potential ofSchwann cells is inspires hope for a significant expansion of therapeutic possibilities inthe treatment of peripheral nerve injuries in the future.
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