Abstract
This study was designed to determine whether the major salivary glands enlarge in chronic lead poisoning in rats, whether lead is deposited preferentially in these glands, and whether inclusion bodies, similar to those found in kidney and liver in lead poisoning, are also found in the salivary glands, the ducts of which have certain similarities to the renal convoluted tubules. No histologic changes were noted in the major salivary glands after the rats had received 1 per cent lead acetate in their drinking water for as long as 212 days, whereas the inclusion bodies were found in the kidney as early as 45 days. The mean dry weights of the parotid glands, expressed as a percentage of the living body weight of the animals, were significantly greater in the experimental animals (17 ± 1.03 mg. per 100 grams) than in the controls (13.7 ± 0.73 mg. per 100 grams), but the other salivary glands showed no such change. Lead was not preferentially concentrated in the parotid or submaxillary glands.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
