Abstract

The salivary gland salivation stimulating peptide was identified from the salivary glands of the migratory locust by its ability to stimulate cAMP production in the same tissue. The gene coding for this peptide has recently been identified and been shown to code for a precursor consisting of a signal peptide, several copies of the peptide separated by Lys–Arg doublets and a few other peptides. These data are consistent with it being a neuropeptide. However, antiserum raised to this peptide labels the acini of the salivary glands while RT-PCR only gives positive results in the salivary gland, but not in any ganglion of the central nervous system. Thus, this peptide is not a typical neuropeptide as previously assumed.

Highlights

  • Insect neuropeptides are interesting for two different reasons

  • As insects are becoming increasingly resistant to classical pesticides, novel insecticides are constantly needed and it is has repeatedly been suggested that agonists or antagonists of insect neuropeptide receptors might offer a solution (Audsley & Down, 2015; Van Hiel et al, 2010)

  • Locusts Adult and fifth instar Locusta migratoria were purchased at a local pet store

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Summary

Introduction

Insect neuropeptides are interesting for two different reasons. On the one hand, insects are protostomes, while vertebrates are deuterostomes. How to cite this article Veenstra (2017), The salivary gland salivation stimulating peptide from Locusta migratoria (Lom-SG-SASP) is not a typical neuropeptide.

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