Abstract
s / Biol Blood Marrow Transplant 19 (2013) S233eS256 S255 compared to 19% (CI95 11.8, 26.1%) (P < .0001) for those who did not have LI at 1 month postAlloHSCT. On multivariate analysis, only bloodstream bacterial infections (P 1⁄4 .0059) and invasive fungal infections (P 1⁄4 .0020) were significant risk factors for developing LI at 1 month. On multivariate analysis for risk factors for TRM, only LI at 1 month postAlloHSCT (P 1⁄4 .0001), primary graft failure (P 1⁄4 .0096) and bloodstream bacterial infections (P 1⁄4 .0328) were significant. However, LI prior to AlloHSCT conditioning was not associated with higher TRM. Conclusions: TRM among pediatric patients with LI at 1 month post-AlloHSCT is extremely high, with infections being the primary risk factor for LI.
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