The Safety and Feasibility of Endoscopic Ultrasound Guided Fine Needle Injection (EUS-FNI) of Local Biologic Anti-Tumor Agents (BAA) in Patients with Advanced Pancreatic Carcinoma (APC)

Abstract

Background: Despite numerous trials evaluating a variety of chemotherapeutic agents, the prognosis of pancreatic cancer remains poor. The recent development of BAA has lead to the possibility of augmenting these treatments. EUS-FNI allows for the local delivery of a variety of antitumor therapies, including BAA, in the treatment of APC. Aim: The purpose of this study was to determine the safety and feasibility of using EUS-FNI for delivering BAA in patients with APC. Methods: We retrospectively identified all patients at our institution from 5/95 to 11/07 receiving EUS-FNI with BAA for the treatment of APC.