The Safety and Efficacy of Different Endovascular Treatments for In-Stent Restenosis of the Femoropopliteal Artery: A Network Meta-analysis

Abstract

Review of the MEDLINE, Embase, Web of Science, and Cochrane databases through February 1, 2021. There were 1348 patients from 14 eligible studies (10 prospective, randomized; 4 retrospective) with femoropopliteal artery in-stent restenosis (FP-ISR) who underwent plain old balloon angioplasty (POBA), drug-coated balloon angioplasty (DCBA), peripheral cutting balloon angioplasty, Viabahn endoprosthesis, directional atherectomy, excimer laser atherectomy, and combination therapy. Technical success rates were significantly higher for Viabahn endoprosthesis than for DCBA and POBA alone. The 1-year primary patency rates were significantly higher for excimer laser atherectomy plus DCBA than excimer laser atherectomy plus POBA and POBA alone. Excimer laser atherectomy plus DCB showed encouraging results regarding one-year primary patency rates for femoropopliteal in-stent restenosis.