Abstract

Abstract 1. 1. Cultures from acute post-traumatic lacerations were taken after wound excision and irrigation in twenty successive patients. Sixteen of these were sterile cultures. Two mild infections developed in association with the four positive cultures. 2. 2. Cultures were obtained from the wounds of 546 patients undergoing surgery in the hospital operating room. One hundred thirty-four positive cultures were obtained. Ninety-seven of the positive cultures were Staph. albus. 3. 3. Five wound infections occurred in the 134 positive cultures from hospital patients. Three of these cultured E. coli, and two cultured alpha hemolytic streptococcus. The identical organism was found in the surgical wound at the time of closure, and in the drainage of the subsequent wound infection. 4. 4. Bacteria present in the surgical wound at the time of closure are the origin of wound infections. 5. 5. Antibiotics will not prevent wound infections in surgical patients but meticulous aseptic surgical technic will.

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