The roles of purple sweet potato anthocyanins in optimizing dietary intervention of metabolic dysfunction-associated fatty liver disease

Abstract

Link of Video Abstract: https://youtu.be/rRJRhubdmcM Metabolic-associated fatty liver disease (MAFLD) is a multifactorial metabolic disorder with complex pathogenesis and a broad spectrum of disease. It is characterized by the accumulation of triglycerides (TG) in hepatocytes, which are associated with hepatic steatosis. Purple sweet potato (Ipomoea batatas L.) (PSP) tuber, is rich in anthocyanin contents. This review aims to discuss recent findings on the effects of purple sweet potato tubers and its potential therapeutic action on MAFLD. In various in vivo studies and limited clinical trials on patients, purple sweet potatoes have been shown to be beneficial not only in lipid metabolism but also in reducing liver fat deposition and insulin resistance. In addition to antioxidant, anti-inflammatory, and anti-hyperlipidemic effects, anthocyanins can be considered as important adjuvant therapeutic agents in the attenuation of inflammation, free radicals, insulin resistance, and hepatocyte injury.